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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC1 All Species: 38.48
Human Site: T1474 Identified Species: 76.97
UniProt: P33527 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33527 NP_004987.2 1531 171561 T1474 L I Q S T I R T Q F E D C T V
Chimpanzee Pan troglodytes XP_001145351 1247 137800 Q1191 I Q S T I R T Q F E D C T V L
Rhesus Macaque Macaca mulatta XP_001094709 1612 178491 T1555 L I Q A T I R T Q F D T C T V
Dog Lupus familis XP_548204 1523 168842 T1466 F I Q A T I R T Q F E S C T V
Cat Felis silvestris
Mouse Mus musculus O35379 1528 171166 T1471 L I Q S T I R T Q F E D C T V
Rat Rattus norvegicus Q8CG09 1532 171475 T1475 L I Q S T I R T Q F E D S T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517193 1537 172363 T1480 L I Q S T I R T Q F D D C T V
Chicken Gallus gallus Q5F364 1525 170953 S1468 L I Q S T I K S Q F E E C T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341895 1518 169232 T1461 L I Q S T I R T Q F E D C T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995704 1548 173512 T1490 L I Q K T I R T E F K E C T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42093 1623 182111 E1423 L I Q K T I R E E F K S C T M
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 T1454 V V Q E T I R T A F K D R T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.5 54.1 56.6 N.A. 88.1 87.4 N.A. 84.2 77.6 N.A. 70.5 N.A. 51.2 N.A. N.A. N.A.
Protein Similarity: 100 80.1 71 74.1 N.A. 94.7 93.8 N.A. 91.7 89.2 N.A. 83.2 N.A. 68.5 N.A. N.A. N.A.
P-Site Identity: 100 0 80 80 N.A. 100 93.3 N.A. 93.3 80 N.A. 100 N.A. 73.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 93.3 86.6 N.A. 100 93.3 N.A. 100 100 N.A. 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.2 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 51.8 59.3 N.A.
P-Site Identity: N.A. N.A. N.A. 60 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 75 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 25 50 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 9 17 9 50 17 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 92 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 84 0 0 9 92 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 17 0 0 9 0 0 0 25 0 0 0 0 % K
% Leu: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 92 0 0 0 0 9 67 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 84 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 9 50 0 0 0 9 0 0 0 17 9 0 0 % S
% Thr: 0 0 0 9 92 0 9 75 0 0 0 9 9 92 0 % T
% Val: 9 9 0 0 0 0 0 0 0 0 0 0 0 9 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _